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Polymorphisms of rs2483205 and rs562556 in the PCSK9 gene are associated with coronary artery disease and cardiovascular risk factors

PCSK9 plays a crucial role in lipid metabolism. This case-control study explored the associations of novel single nucleotide polymorphisms (SNPs) of the PCSK9 gene with coronary artery disease (CAD) (≥ 1 ..... see more

Source : https://www.nature.com/articles/s41598-021-90975-0

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Pcsk9 is associated with severity of coronary artery lesions in male patients with premature myocardial infarction

Background Proprotein convertase subtilisin/kexin type 9 (Pcsk9) correlated with incidence and prognosis of coronary heart disease. However, it is unclear whether Pcsk9 contributed to coronary artery lesion severity in patients ..... see more

Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-021-01478-w

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Effect of L-carnitine supplementation on lipid profile and apolipoproteins in children on hemodialysis: a randomized placebo-controlled clinical trial

Background Cardiovascular disease (CVD) is the leading cause of death in children with chronic kidney disease (CKD) and accounts for 40% of all deaths among pediatric patients with stage 5 ..... see more

Source : https://link.springer.com/article/10.1007/s00467-021-05080-1

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Safety and Efficacy of a Beverage Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Lipid Status in Healthy Subjects: An Intervention Study (the Lupine‐1 Trial)

Ivan Cruz-Chamorro , Guillermo Santos-Sánchez , María Carmen Millán-Linares , Alicia Martínez-López , Patricia Judith Lardone , Ignacio Bejarano , Juan Miguel Guerrero , Antonio Carrillo-Vico , Corresponding Author Instituto ..... see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.202100139

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Clinical Significance of the Cardio-Ankle Vascular Index in Postmenopausal Women With Hypercholesterolemia | Hitsumoto | Journal of Clinical Medicine Research

Abstract Background: The cardio-ankle vascular index (CAVI) is a physiological indicator of arterial elasticity. However, limited information regarding the clinical significance of the CAVI in patients with hypercholesterolemia is available. ..... see more

Source : https://www.jocmr.org/index.php/JOCMR/article/view/4509

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Comparing impact of SGLT2 inhibitors and GLP-1 agonists on lipid profile among the patients with diabetes mellitus Type 2. Results of a prospective 18-week observational study

1Tbilisi Heart and Vascular Clinic, Tblisi, Gerogia; 2National institute of Endocrinology, Tblisi, Georgia; 3Clinic 'ENMEDIC', Tblisi, Georgia; 4 'Family Doctor', Tblisi, Georgia Background In Georgia, significantly huge number of patients ..... see more

Source : https://www.endocrine-abstracts.org/ea/0073/ea0073aep305

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PRIME PubMed | The combination of sesamol and clofibric acid moieties leads to a novel potent hypolipidemic agent with antioxidant, anti-inflammatory and hepatoprotective activity

Oxidative stress and inflammation have been considered the main factors in the liver injury of clofibrate (CF). To obtain a novel antihyperlipidemic agent with antioxidant, anti-inflammation and hepatoprotection, the combination ..... see more

Source : https://www.unboundmedicine.com/medline/citation/34015506/The_combination_of_sesamol_and_clofibric_acid_moieties_leads_to_a_novel_potent_hypolipidemic_agent_with_antioxidant

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Changes in the blink reflex during migraine with aura and the inter-attack period Ates MP, Ferik S, Pektezel LD, Guven H, Comoğlu SS, - J Indian Prosthodont Soc

Changes in the blink reflex during migraine with aura and the inter-attack period Mehlika Panpalli Ates 1, Sevgi Ferik 2, Leyla Das Pektezel 3, Hayat Guven 1 Department of Neurology, ..... see more

Source : https://www.nsnjournal.org/preprintarticle.asp?id=315948;type=0

A 66 year old female college professor is seen in your office after undergoing an ‘executive physical’ which included an EKG, GXT, and coronary calcium score. She is asymptomatic, ..... see more

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  • from Doctor Unite 2 weeks 5 days
    As she now has confirmed atherosclerosis, she needs to initiate statin therapy and daily ASA 81mg. I recommend starting rosuvastatin, which has the best data for reduction of CV event Show More
  • from Generation NP 2 weeks 6 days
    There probably isn't a lot of improvement she can do with diet, although a plant based diet can still be carb and fat heavy. I have found rosuvastatin to be Show More
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A Successful Treatment of Chronic Migraine with Hyperbaric Oxygen Therapy - European Medical Journal

Download as | PDF Authors: Rahmah Shafee, Mohd Amirullah Hamzah, Rajesh Kumar Muniandy 1 1 2 Disclosure: The authors have declared no conflicts of interest. Received: 20.03.20 Accepted: 08.01.21 Citation ..... see more

Source : https://www.emjreviews.com/neurology/article/a-successful-treatment-of-chronic-migraine-with-hyperbaric-oxygen-therapy/

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A Novel Approach to Defining Success in the Acute Treatment of Migraine: Pooled Results From the ACHIEVE I and ACHIEVE II Trials (1528)

Objective: To evaluate an alternative method of characterizing success in acute migraine treatment. Background: Migraine is characterized by a symptom complex comprising head pain, associated symptoms, and functional disability in ..... see more

Source : https://n.neurology.org/content/96/15_Supplement/1528.abstract

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Cholesterol-Lowering Statins Prescribed Less Later in Day

Newswise - PHILADELPHIA- Furthering efforts to understand why potentially life-saving statins are so under-prescribed among American patients with heart disease, a new study shows that clinicians are more likely to ..... see more

Source : https://www.newswise.com/articles/cholesterol-lowering-statins-prescribed-less-later-in-day

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Topic review Berberine Subjects: Others

Topic review Definition Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids withstrong biological and pharmacological activity. Currently, berberine is receiving considerable interest due to its anticancer ..... see more

Source : https://encyclopedia.pub/item/revision/ee457257842a32f4861784500ce8bbc8

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Associations of genetic variants of lysophosphatidylcholine metabolic enzymes with levels of serum lipids

Metabolic disturbance of lysophosphatidylcholine (LPC) is related with dyslipidemia. Therefore, eight single-nucleotide polymorphisms (SNPs) were selected from LPC metabolic enzymes to study their associations with obesity and serum levels of ..... see more

Source : https://www.nature.com/articles/s41390-021-01549-9

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Association between baseline LDL-C and prognosis among patients with coronary artery disease and advanced kidney disease

Background Lower low-density lipoprotein cholesterol (LDL-C) is significantly associated with improved prognosis in patients with coronary artery disease (CAD). However, LDL-C reduction does not decrease all-cause mortality among CAD patients ..... see more

Source : https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-021-02375-1