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Familial hypercholesterolaemia: Experience of a tertiary paediatric lipid clinic

Corresponding Author Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, New South Wales, Australia Correspondence: Dr Jeffrey Yeung, Institute of Endocrinology and Diabetes, The Children's Hospital at ..... see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/jpc.15426

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Malondialdehyde-Modified Low-Density Lipoprotein Is a Useful Marker to Identify Patients With Vulnerable Plaque | Request PDF

Request PDF | Malondialdehyde-Modified Low-Density Lipoprotein Is a Useful Marker to Identify Patients With Vulnerable Plaque | Background: The association between elevated malondialdehyde-modified low-density lipoprotein (MDA-LDL) and plaque instability in ..... see more

Source : https://www.researchgate.net/publication/229074271_Malondialdehyde-Modified_Low-Density_Lipoprotein_Is_a_Useful_Marker_to_Identify_Patients_With_Vulnerable_Plaque

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Association of baseline as well as change in lipid levels with the risk of cardiovascular diseases and all-cause deaths - PubMed

High baseline atherogenic lipid level has been an established risk factor for the risk of cardiovascular events. Evidence concerning the role of lipid changes in cardiovascular and death risks are ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33795701/

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Intensive low-density lipoprotein cholesterol lowering in cardiovascular disease prevention: opportunities and challenges

Elevated levels of low-density lipoprotein cholesterol (LDL-C) are associated with increased risk of coronary heart disease and stroke. Guidelines for the management of dyslipidaemia from the European Society of Cardiology ..... see more

Source : https://heart.bmj.com/content/early/2021/03/31/heartjnl-2020-318760.abstract

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Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci

Author summary We utilized the unprecedentedly large genotype and phenotype dataset in the UK Biobank to perform a genome-wide association study (GWAS) which accounts for the interplay between genotype and ..... see more

Source : https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009431

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Clinical Importance of the LDL-C/Apolipoprotein B Ratio for Neointimal Formation after Everolimus-Eluting Stent Implantations - PubMed

A low LDL-C/Apo B ratio was found to be strongly associated with neointimal proliferation and neointimal instability evidenced chronically by OCT and CAS. An LDL-C/Apo B ≤ 1.2 will be ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33746158/

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Similar major cardiovascular outcomes between pure statin and ezetimibe-statin in comparable intensity for type 2 diabetes with extremely atherosclerotic risks

Atorvastatin 40 mg (ATOR 40) and ezetimibe 10 mg/simvastatin 20 mg (EZ-SIM 20) have similar reductions of low-density lipoprotein cholesterol (LDL-C) but cardiovascular (CV) outcomes between these two therapies are ..... see more

Source : https://www.nature.com/articles/s41598-021-86090-9

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LDL/HDL cholesterol ratio is associated with new-onset NAFLD in Chinese non-obese people with normal lipids: a 5-year longitudinal cohort study

Background Low-density lipoprotein to high density lipoprotein (LDL/HDL) cholesterol ratio has been reported to predict the risk of many metabolic diseases. However, the association between the LDL/HDL cholesterol ratio and ..... see more

Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-021-01457-1

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Impact of Major Cardiovascular Risk Factors on the Incidence of Cardiovascular Disease among Overweight and Non-Overweight Individuals: The Circulatory Risk in Communities Study (CIRCS).

Aim We aimed to examine the impact of high-risk levels of cardiovascular risk factors on the incidence of cardiovascular disease (CVD) in overweight and non-overweight individuals without treatment for the ..... see more

Source : https://europepmc.org/article/med/33731540

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Compatibility between an overnight fasting and random cholesterol tests in Asians

Recent Western guidelines recommend non-fasting lipid profiles to manage dyslipidaemia. We explored its applicability to an Asian population. We determined the differences between an overnight fasting and non-fasting cholesterol profiles ..... see more

Source : https://www.nature.com/articles/s41598-021-85914-y

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  • from Endocrinologist Nation 1 month 2 weeks
    There are many pts who cannot tolerate statins, it’s exciting to see new therapies on horizon! I was not aware of this medication, I’m glad I learned something new today
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Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19

The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known ..... see more

Source : https://www.nature.com/articles/s41467-021-21553-1

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Prestroke Statins Improve Prognosis of Atrial Fibrillation-Associated Stroke through Increasing Suppressor of Cytokine Signaling-3 Levels - PubMed

doi: 10.1159/000513767. Online ahead of print. 1 Department of Neurology, Chengdu Second People's Hospital, Chengdu, China, lutaoli286@sina.com. 2 Department of Neurology, Nanchong Central Hospital, Nanchong, China. 3 Department of Neurology, ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33684912/