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Understanding Strengths and Limitations of Different Methods of LDL-C Estimation - American College of Cardiology

Understanding Strengths and Limitations of Different Methods of LDL-C Estimation - American College of Cardiology

Source : https://www.acc.org/latest-in-cardiology/articles/2019/04/02/13/21/understanding-strengths-and-limitations-of-different-methods-of-ldl-c-estimation

Low-density lipoprotein-cholesterol (LDL-C) remains a key contributor to plaque formation and atherosclerotic cardiovascular disease (ASCVD). Measuring LDL-C by gold standard ultracentrifugation is time-intensive and expensive. As such, the Friedewald equation, an estimate of LDL-C initially intended for research purposes, has been utilized over the past 50 years as a primary method for clinically estimating LDL-C.

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