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Forty-Two-Year-Old Male With Family History of Coronary Heart Disease

A 42-year-old male whose father and both grandfathers all had a myocardial infarction in their late 40s presents to you with concerns about repeating his family history. Though he currently has no complaints, he is concerned because each man died in his early to mid 50s.

A fasting lab including lipid panel revealed a low HDL-C of 21 mg/dL. When this result is combined with the man's family history of premature congenital heart disease, what is your recommendation regarding medication including statins? When should he follow up with you and which tests will you run?