Key Points
• Conclusion/Relevance: “[In] addition to conventional parameters, the estimation of ox-LDL [oxidized LDL], RLP-C [remnant lipoprotein cholesterol] and hs-CRP [high-sensitive C-reactive protein] can prove to be a valuable tool in risk assessment of population and management of the disease. Our results suggesting the link between the level of high ox-LDL along with remnant lipoprotein cholesterol and hs-CRP may [be] consistent with atherogenesis in subject[s] with CHD [coronary heart disease[.”
• In this cross-sectional study, Indian investigators assessed lipid profiles, oxidized LDL, and hs-CRP levels in 91 CHD patients and 91 healthy controls aged between 25 and 55 years. They found that all variables were increased. They also noted a negative correlation between oxidized LDL and HDL-C.
• The authors noted that RLP-C and ox-LDL levels are related to local and systemic inflammation, which in turn predicts CHD.
• Limitations of this study include its small sample size and a limited understanding of ox-LDL, RLP-C, and hs-CRP.
• Conclusion/Relevance: “[In] addition to conventional parameters, the estimation of ox-LDL [oxidized LDL], RLP-C [remnant lipoprotein cholesterol] and hs-CRP [high-sensitive C-reactive protein] can prove to be a valuable tool in risk assessment of population and management of the disease. Our results suggesting the link between the level of high ox-LDL along with remnant lipoprotein cholesterol and hs-CRP may [be] consistent with atherogenesis in subject[s] with CHD [coronary heart disease[.”
• In this cross-sectional study, Indian investigators assessed lipid profiles, oxidized LDL, and hs-CRP levels in 91 CHD patients and 91 healthy controls aged between 25 and 55 years. They found that all variables were increased. They also noted a negative correlation between oxidized LDL and HDL-C.
• The authors noted that RLP-C and ox-LDL levels are related to local and systemic inflammation, which in turn predicts CHD.
• Limitations of this study include its small sample size and a limited understanding of ox-LDL, RLP-C, and hs-CRP.