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Bempedoic Acid, the Next LDL Cholesterol-Lowering Medication to Join the Arsenal? Insights From the CLEAR Wisdom Trial - American College of Cardiology

Bempedoic Acid, the Next LDL Cholesterol-Lowering Medication to Join the Arsenal? Insights From the CLEAR Wisdom Trial - American College of Cardiology

Source : https://www.acc.org/latest-in-cardiology/articles/2019/05/03/10/20/bempedoic-acid-the-next-ldl-cholesterol-lowering-medication-to-join-the-arsenal

Recent developments in low-density lipoprotein cholesterol (LDL-C) lowering could mean even more treatment options for our patients. The mainstay, statin therapy, acts on HMG-CoA reductase to reduce cholesterol synthesis, in turn increasing LDL-receptor (LDL-R) expression and LDL catabolism. At high intensity doses, statins are highly efficacious in lowering LDL-C, offering a reduction of 50% or more.

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