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Lipoprotein(a) is associated with the onset but not the progression of aortic valve calcification - PubMed

Lipoprotein(a) is associated with the onset but not the progression of aortic valve calcification - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35869873/

doi: 10.1093/eurheartj/ehac377. Online ahead of print. 1 Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. 2 Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. 3 Department of Radiology & Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.


Conclusion/Relevance: In the population-based Rotterdam Study, Lp(a) is robustly associated with baseline and new-onset AVC but not with AVC progression, suggesting that Lp(a)-lowering interventions may be most effective in pre-calcific stages of aortic valve disease.