A pragmatic clinical trial of cascade testing for familial hypercholesterolemia
Source : https://www.gimjournal.org/article/S1098-3600(22)00917-0/fulltext
Genomics in public health: perspective from the Office of Public Health Genomics at the Centers for Disease Control and Prevention (CDC). : 830-837 https://doi.org/10.3390/healthcare3030830 Correction: A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health.
Conclusions: New case detection rate was significantly higher in FH families with a monogenic etiology than in those without such an etiology owing to greater uptake and yield of cascade testing.