Impact of TAVR on coronary artery hemodynamics using clinical measurements and image‐based patient‐specific in silico modeling - Scientific Reports
Source : https://www.nature.com/articles/s41598-023-31987-w
In recent years, transcatheter aortic valve replacement (TAVR) has become the leading method for treating aortic stenosis. While the procedure has improved dramatically in the past decade, there are still...
Discussion: In this paper, we develop a novel LPM which utilizes non-invasive inputs to simulate blood flow waveforms in the main proximal coronary branches (LAD, LCX and RCA) as well as other global cardiovascular hemodynamic parameters. The model was then applied to 19 patients undergoing TAVR to examine the impact of the procedure on...
Surgical Aortic Valve Replacement to Treat Prosthetic Valve Endocarditis After Valve-in-Valve Transcatheter Aortic Valve Replacement
Prosthetic valve endocarditis (PVE) is an uncommon complication after heart valve replacement surgery that can result in increased morbidity and mortality. Current guidelines for management of PVE recommend antibiotic therapy...
Conclusions: With an aging population, the volume of aortic valve interventions will continue to rise; consequently, there will likely be a concomitant increase in PVE. It would be prudent to gain an understanding of whether ViV TAVR is a viable choice for select high-risk patients with PVE. Further investigation is warranted to help...
Outcomes and Hemodynamic Performances of Transcatheter Aortic Valve Replacement with Two Generations of Self-Expanding Transcatheter Aortic Valves - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37229330/
Advancements in transcatheter valve technologies have resulted in improved outcomes for patients undergoing TAVR with self-expanding valves. With the new-generation Evolut R, device success was high and the 30-day composite...
Conclusions: Advancements in transcatheter valve technologies have resulted in improved outcomes for patients undergoing TAVR with self-expanding valves. With the new-generation Evolut R, device success was high and the 30-day composite safety endpoint was significantly reduced after TAVR compared with CoreValve.
Impact of osteoporotic risk in women undergoing transcatheter aortic valve replacement - Cardiovascular Intervention and Therapeutics
Source : https://link.springer.com/article/10.1007/s12928-023-00940-z
Low body weight and advanced age are reported to be among the best predictors of osteoporosis, and osteoporosis self-assessment tool (OST) values are calculated using a simple formula to identify...
Relevance: In our recent study, we demonstrated an association between fractures and poor outcomes in postmenopausal women following transcatheter aortic valve replacement (TAVR). In this study, we aimed to investigate the osteoporotic risk in women with severe aortic stenosis and determined whether an OST could predict all-cause mortality...
Impact of Long-Term Steroid Use on the Disposition of Patients Undergoing Transcatheter Aortic Valve Replacement: A Retrospective Nationwide Sample Analysis
Background Chronic steroid use is debilitating to health, but, in some cases, it is necessary. We examined the effect of chronic steroid use on the discharge disposition of people undergoing...
Conclusion: The comorbidity burden of individuals on long-term steroids undergoing TAVR was slightly higher than those not on steroids undergoing TAVR. Despite this, there was no statistically significant difference in their hospital outcomes following TAVR with respect to dispositions.