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2yr
High-Risk Admission Prior to Transcatheter Aortic Valve Replacement and Subsequent Outcomes: Preceding Events and Outcomes After TAVR

High-Risk Admission Prior to Transcatheter Aortic Valve Replacement and Subsequent Outcomes: Preceding Events and Outcomes After TAVR

Source : https://www.sciencedirect.com/science/article/pii/S0002870323003113?via=ihub

Severe, symptomatic aortic stenosis may cause heart failure, acute myocardial infarction, or syncope; limited data exist on the occurrence of such events.

In this nonrandomized observational study, researchers found that hospitalization for HF, acute MI, or syncope before TAVR were associated with a higher risk of death and CV or all-cause hospitalization after TAVR.

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2yr
Making all the right moves with TAVR

Every move in chess is crucial, especially the first move. Similarly, it’s crucial to choose the right TAVR platform for the index procedure to ensure successful lifetime management for your patients.

Successful lifetime management with TAVR depends on:

  • Consistent clinical outcomes starting with the index procedure
  • Robust valve durability that enhances long-term outcomes
  • Design that allows for future interventions

Experts recommend that any TAVR platform should offer successful lifetime management. Outcomes should be reliable despite patient anatomy, location, and valve size. The design should target non-structural and structural drivers of reintervention, such as mitigating calcification, a leading cause to valve failure. Lastly, TAVR platforms need to provide coronary access and options for re-do procedures.

What valve is your first choice for TAVR and why?

  • 2yr
    Well, as an electrophysiologist referring patients for TAVR and seeing patients after TAVR, it seems like the Edwards sapien valve is the most popular among my interventionists. This has Show More
  • 2yr
    I would say Edwards Sapien 3 is our most commonly implanted valve given data and outcomes. The structural team does the decision making re specific valve implant.

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2yr
Association Between Serum Testosterone and Aortic Valve Stenosis: a Prospective Cohort Study

Association Between Serum Testosterone and Aortic Valve Stenosis: a Prospective Cohort Study

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671969/

Serum testosterone is associated with atherosclerotic cardiovascular disease, which shares risk factors with aortic stenosis (AS). The association between serum testosterone and AS has not been previously investigated.

Increased levels of serum testosterone were associated with an increased risk of aortic stenosis independently of several established CV risk factors.

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2yr
Midterm Survival of Low-Risk Patients Treated With Transcatheter Versus Surgical Aortic Valve Replacement: Meta-Analysis of Reconstructed Time-to-Event Data

Midterm Survival of Low-Risk Patients Treated With Transcatheter Versus Surgical Aortic Valve Replacement: Meta-Analysis of Reconstructed Time-to-Event Data

Source : https://pubmed.ncbi.nlm.nih.gov/37929669/

We performed a meta-analysis of reconstructed time-to-event data from randomized controlled trials (RCTs) and propensity-score matched (PSM) studies comparing transcatheter versus surgical aortic valve replacement (TAVR versus SAVR) to evaluate...

Compared with TAVR, SAVR appeared to be associated with improved survival beyond 2 years in low-risk patients, but this survival benefit was observed only in propensity-score matched studies and not in randomized control trials.

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2yr

A recent article in JACC outlines the continued large disconnect between the number of patients with significant aortic stenosis and the number of patients actually being treated. As always, the call is for "more research". But what do those of us who see these echos and often these patients think can be done to bring more people forward for...

The Mortality Burden of Untreated Aortic Stenosis - American College of Cardiology

The Mortality Burden of Untreated Aortic Stenosis - American College of Cardiology

Source : https://www.acc.org/Latest-in-Cardiology/Journal-Scans/2023/10/23/16/01/the-mortality-burden-tct-2023

David S. Bach, MD, FACC