Predictors of Conduction Disturbances after Transcatheter Aortic Valve Implantation with Balloon-expandable Valve for Bicuspid Aortic Valve Stenosis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35543515/
The implantation depth - MS length, and severe LVOT calcification predicted new-onset CD following TAVR in BAV with balloon-expandable valve. Among BAV patients, THV were implanted more deeply compared to...
Conclusion: The implantation depth - MS length, and severe LVOT calcification predicted new-onset CD following TAVR in BAV with balloon-expandable valve. Among BAV patients, THV were implanted more deeply compared to THV patients. High deployment technique could be considered to avoid new-onset CD in BAV anatomy.
Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification
Source : https://www.sciencedirect.com/science/article/pii/S2452302X21004277?via=ihub
The neuropilin-like protein, DCBLD2, is down-regulated in aortic valves of patients undergoing valve replacement for aortic stenosis. * About 50% of DCBLD2-deficient mice develop bicuspid aortic valve. These animals have...
Relevance: Introducing a clinically relevant model of calcific aortic valve disease, these findings may explain how a combination of genetic background and bicuspid aortic valve promotes aortic valve calcification and stenosis.
Mechanical Circulatory Support Options in Patients With Aortic Valve Pathology - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35545462/
Mechanical circulatory support (MCS) is used in cardiogenic shock for periprocedural hemodynamic stability in high-risk patients and to support patients with symptomatic coronary artery disease. Depending on the MCS type,...
Conclusion/Relevance: The presence of aortic valve (AV) abnormalities, such as aortic stenosis, aortic insufficiency, replaced AVs, or AV masses, adds even further to the challenge of selecting the appropriate support strategy. In this narrative review, a concise review of MCS options and the special considerations for various AV pathologies...
Quality of life and frailty outcomes following surgical and transcatheter aortic valve replacement - Journal of Cardiothoracic Surgery
Source : https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-022-01876-w
Background Our objective was to report on the prospective outcomes in the areas of depression, quality of life, angina, and frailty in SAVR and TAVR patients with aortic stenosis undergoing...
Conclusions: This 12 months follow up of cardiac surgical patients has revealed significant improvement in PROMs and frailty in all groups by 3 months postoperative regardless of surgical or transcatheter approach. Outcome measures of quality of life and frailty could be utilized as a measure of outcome more regularly in patients undergoing...
Late Outcomes of Transcatheter Aortic Valve Implantation in Bicuspid Versus Tricuspid Valves: Meta-Analysis of Reconstructed Time-To-Event Data - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35513298/
Based on previous meta-analyses including immediate/1-year results, individuals with bicuspid aortic valve (BAV) stenosis can undergo TAVI with similar outcomes as those with tricuspid aortic valve (TAV), but with higher...
Conclusion: In patients with selected BAV anatomy deemed favorable for TAVI, we did not find worse survival over time in comparison with patients with TAV; however, the follow-up beyond 1 year remains limited in the studies and we need more investigation for specific bicuspid anatomies with longer follow-up. Most importantly, randomized...