Comparison of short and long forms of the Flinders program of chronic disease SELF-management for participants starting SGLT-2 inhibitors for congestive heart failure (SELFMAN-HF): protocol for a prospective, observational study
Source : https://www.frontiersin.org/articles/10.3389/fmed.2023.1059735/full
IntroductionCongestive heart failure (CHF) causes significant morbidity and mortality. It is an epidemic, and costs are escalating. CHF is a chronic disease whose trajectory includes stable phases, periods of decompensation,...
Conclusion: The specific challenges highlighted will be addressed in the creation of hypotheses for future studies. Areas that will be challenging include the CDSM programme for clients from diverse/lower educational and socioeconomic backgrounds where the programme may have variable effectiveness. Delivery to clients placed at the apex of...
Sex differences in cardiovascular outcomes of SGLT-2 inhibitors in heart failure randomized controlled trials: A systematic review and meta-analysis
Source : https://www.sciencedirect.com/science/article/pii/S2666602223000137?via=ihub
In patients with heart failure (HF), randomized controlled trials (RCTs) of sodium-glucose transporter-2 inhibitors (SGLT-2is) have proven to be effec...
Conclusion: SGLT-2is reduce the risk of primary composite outcomes in patients with HF, regardless of sex; however, the benefits were less pronounced in women. Further research needs to be done to better explain these observed differences in outcomes.
Liver tests, cardiovascular outcomes and effects of empagliflozin in patients with heart failure and preserved ejection fraction: the EMPEROR-Preserved Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37278451/
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Cost-Effectiveness of Dapagliflozin vs Empagliflozin for Treating Heart Failure With Reduced Ejection Fraction in the United States - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37270374/
The findings of this study indicate that dapagliflozin may offer greater lifetime economic value when compared with empagliflozin. Given that the current clinical practice guideline does not recommend one SGLT2...
Multimodality Imaging and Biomarker Approach to Characterize the Pathophysiology of Heart Failure in Left Ventricular Non-Compaction with Preserved Ejection Fraction - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37297827/
LVNC patients with HFpEF have diffuse fibrosis, which is more extensive at the apical level, explaining the decrease in apical deformation and overexpression of Galectin-3. Lower transmural and base-to-apex deformation...