Novel Strategies to Improve Prescription of Guideline-Directed Medical Therapy in Heart Failure - Current Treatment Options in Cardiovascular Medicine
Source : https://link.springer.com/article/10.1007/s11936-023-00979-4
Purpose of review To examine the emerging data for novel strategies being studied to improve use and dose titration of guideline-directed medical therapy (GDMT) for patients with heart failure (HF)....
Relevance: A large therapeutic gap between guideline-directed recommendations and real-world practice exists in the contemporary management of patients with HFrEF. Many strategies are being developed in an attempt to close this gap, as outlined in this review.
Transcatheter Aortic Valve Replacement for Aortic Valve Infective Endocarditis: A Systematic Review and Call for Action - Cardiology and Therapy
Source : https://link.springer.com/article/10.1007/s40119-023-00314-9
We aimed to systematically analyze the literature on the use of transcatheter aortic valve replacement (TAVR) to treat active aortic valve infective endocarditis (AV-IE). Surgery is declined in one-third of...
Effect of Dapagliflozin Versus Empagliflozin on Cardiovascular Death in Patients with Heart Failure Across the Spectrum of Ejection Fraction: Cost per Outcome Analysis - American Journal of Cardiovascular Drugs
Source : https://link.springer.com/article/10.1007/s40256-023-00578-5
Background Dapagliflozin and empagliflozin have shown clinical benefits in patients with heart failure (HF). Their comparative monetary value remains undetermined, and we therefore sought to compare the cost-per-outcome implications of...
Empagliflozin in heart failure with preserved ejection fraction with and without atrial fibrillation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37062866/
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Tumor necrosis factor-α mediates inflammation-induced early-stage left ventricular systolic dysfunction
Source : https://journals.lww.com/cardiovascularpharm/Abstract/9900/Tumor_necrosis_factor___mediates.172.aspx
We have previously shown that rats with collagen-induced arthritis (CIA) have systemic inflammation, LV diastolic dysfunction, and that increased circulating TNF-α contributes to inflammation-induced HFpEF pathogenesis, but does not mediate...