The role of thrombin in the paradoxical interplay of cancer metastasis and the vascular system: A driving dynamic - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40215647/
The coagulation system plays a complex role in cancer therapy. Endothelial damage and tissue factor increased by chemotherapy initiate the coagulation cascade, producing active FXa and releasing thrombin. Thrombin triggers...
Chemotherapy-induced coagulation promotes tumor spread. Dual inhibition of FXa and plasmin, including tranexamic acid with NOACs, may reduce metastasis without increasing bleeding risk in cancer patients.
Early Albumin Administration in Veno-Arterial Extracorporeal Membrane Oxygenation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39713990/
Early albumin administration in eCPR patients was linked to a significant decline in fluid balance. Moreover, volume therapy with albumin application was an independent predictor for improved survival in eCPR...
Early albumin use in eCPR patients reduced fluid balance and improved survival, showing benefit over crystalloids; no such effect was seen in cardiogenic shock patients on VA ECMO.
Call to action for acute myocardial infarction in women: international multi-disciplinary practical roadmap - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39507804/
Cardiovascular diseases are the leading cause of death among women, and the incidence among younger women has shown the greatest increase over the last decades, in particular for acute myocardial...
Cardiovascular disease in women, especially younger ones, is rising, with worse post-AMI outcomes than men; this study targets improving prevention, diagnosis, treatment, and rehabilitation through tailored toolkits.
Prodromal Symptoms of Acute Myocardial Infarction in Women: A Systematic Review of Current Evidence - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40259795/
No patient or public contribution.
This systematic review identifies unusual fatigue, sleep disturbances, and anxiety as key prodromal symptoms in women before acute coronary syndrome, emphasizing the need for better awareness to improve diagnosis.
Tooth pain accompanying cluster headache in a middle-aged female: A case report - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40092303/
Some orofacial pains (OFP) resemble primary headache disorders, but involve the trigeminal nerve V2 or V3 dermatome. The International Classification of Orofacial Pain (ICOP) distinguishes three types of such OFPs:...
A 46-year-old woman with persistent toothache and orbital pain, initially diagnosed as Type 1 orofacial pain, progressed to Type 2. The case underscores differentiating nonodontogenic from odontogenic pain for proper treatment.