Cardiac Vagal Nerve Activity During Exercise: New insights and future directions - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40010037/
A new paradigm is emerging in which cardiac vagal nerve activity is maintained and increases during exercise. This paradigm challenges decades of studies that have quoted a withdrawal of cardiac...
A new paradigm suggests cardiac vagal activity increases during exercise, challenging past views. It critiques indirect measurement methods, discusses vagal control variations, and proposes future research directions.
Hybrid rotational atherectomy and shockwave-assisted complex left main PCI with mechanical support in a high-bleeding risk patient, a rare case report - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40318487/
The hybrid PCI approach combining mechanical support and advanced interventional techniques was effective in managing complex coronary artery disease in a high-risk patient contraindicated for CABG. This strategy offers a...
High-risk PCI using Impella and advanced techniques effectively treated complex left main disease in a CABG-ineligible patient, demonstrating a viable, tailored approach for high-risk coronary interventions.
Recurrent Cardiac Tamponade Following Rotablator-Associated Coronary Perforation Treated with Additional Covered Stent Implantation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39828332/
Rotablator-associated coronary perforation can be fatal if bailout is delayed. Successful bailout is typically defined as the disappearance of contrast extravasation after a haemostatic intervention. We report a case of...
Recurrent cardiac tamponade after coronary perforation was caused by covered stent malapposition undetectable by angiography; intravascular ultrasound revealed the issue, guiding successful re-intervention.
The role of thrombin in the paradoxical interplay of cancer metastasis and the vascular system: A driving dynamic - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40215647/
The coagulation system plays a complex role in cancer therapy. Endothelial damage and tissue factor increased by chemotherapy initiate the coagulation cascade, producing active FXa and releasing thrombin. Thrombin triggers...
Chemotherapy-induced coagulation promotes tumor spread. Dual inhibition of FXa and plasmin, including tranexamic acid with NOACs, may reduce metastasis without increasing bleeding risk in cancer patients.
Early Albumin Administration in Veno-Arterial Extracorporeal Membrane Oxygenation - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39713990/
Early albumin administration in eCPR patients was linked to a significant decline in fluid balance. Moreover, volume therapy with albumin application was an independent predictor for improved survival in eCPR...
Early albumin use in eCPR patients reduced fluid balance and improved survival, showing benefit over crystalloids; no such effect was seen in cardiogenic shock patients on VA ECMO.