The Efficacy and Safety of Indobufen-Based DAPT in ACS Patients with a History of Gastrointestinal Damage Undergoing PCI: A Single-Center, Observational Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41729598/
PurposeIndobufen, an alternative to aspirin in acute coronary syndrome (ACS) patients with gastrointestinal damage undergoing percutaneous coronary intervention (PCI), has limited data on its efficacy and safety in long-term use....
In 255 ACS patients with prior gastrointestinal damage undergoing PCI, indobufen-based DAPT reduced major and clinically significant gastrointestinal events versus aspirin-based DAPT, without increasing cardiovascular events, improving symptoms and quality of life.
Reduced haemorrhage during external medial orbital wall decompression with nasal packing containing vasoconstrictive agent - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41708136/
This study demonstrated a highly significant reduction in perioperative bleeding during retrocaruncular medial decompression when nasal packing with a vasoconstrictive agent was used (p<0.001). The main limitation of this study...
Randomized prospective study showed nasal packing with cocaine-adrenaline significantly reduced intraoperative bleeding during external medial orbital wall decompression versus control (9.4g vs 30.1g; p<0.001), without added complications, facilitating surgical visualization.
ST-segment elevation myocardial infarction as the first clue to membranous nephropathy: A case report - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41650082/
Although rare, STEMI may be the initial manifestation of MN. In young patients with myocardial infarction who exhibit clinical features of nephrotic syndrome, a hypercoagulable state should be considered. Early...
This case highlights STEMI as a rare initial presentation of membranous nephropathy in a young adult, emphasizing nephrotic syndrome–related hypercoagulability, recurrent coronary thrombosis risk, and the need for multidisciplinary management.
Safety and Efficacy of Exercise-based Cardiac Rehabilitation in Patients with Refractory Angina - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41637323/
The 12-week ECR-program was safe and effective in improving exercise duration, distance covered and ischemic burden on ESE in patients with RA.
A 12-week exercise-based cardiac rehabilitation program was safe in refractory angina, improving exercise tolerance, angina severity, and ischemic burden versus medical therapy, without increasing major cardiovascular events.
Exercise-mimicking effects of betaine in chronic disease prevention and management - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41608511/
Betaine, a natural compound found in beets, wheat germ, shellfish, and mammalian tissues, plays a crucial role in preventing and treating various chronic diseases. As the global population ages, chronic...
This review explores betaine as an exercise mimetic, detailing its molecular mechanisms and potential to prevent or manage aging-related chronic diseases, especially for individuals unable to exercise.