Cardiovascular Disease Connect
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In established cardiovascular disease, what most commonly prompts a management reassessment?

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Pulmonary indications for heart-lung transplantation: A modified Delphi survey among the French transplantation community. - PubMed

Pulmonary indications for heart-lung transplantation: A modified Delphi survey among the French transplantation community. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42111398

A survey of French experts shows variability in opinions on heart-lung transplantation indications, highlighting the need for personalized, multidisciplinary decision-making in complex cases.


A modified Delphi survey reveals no consensus on pulmonary indications for heart-lung transplantation, highlighting individualized decision-making, especially in severe PAH, right ventricular dysfunction, and congenital heart disease.

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2mo
Cardinal trial: Tonlamarsen shows sustained RAAS suppression and BP reduction in uncontrolled hypertension at ACC 2026

Dr. Luke Laughlin (Preventive Cardiologist, Cleveland Clinic) presented the Cardinal trial at ACC 2026, where Tonlamarsen, an investigational antisense oligonucleotide, reduced angiotensinogen by 67% with ongoing dosing and maintained 23% suppression after a single dose. Despite biochemical differences, both groups achieved similar ~7 mmHg systolic BP reductions, suggesting BP lags behind RAAS suppression. The upcoming Cardinal-ASH study will target acute severe hypertension patients to further evaluate its impact.

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2mo
Cardiac MRI in cardiac dystrophinopathy: recommendations on imaging. - PubMed

Cardiac MRI in cardiac dystrophinopathy: recommendations on imaging. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42161423

Guidelines suggest echocardiography for routine surveillance in DMD, with CMR at critical stages enhancing early detection, including males with BMD and females with DMD-gene variations.


Echocardiography remains primary for cardiac surveillance in DMD, with CMR recommended for early detection at key stages after age 10, including males with BMD and females with DMD-gene variations.

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2mo
Cardiovascular involvement in ankylosing spondylitis and axial spondyloarthritis: epidemiology, mechanisms, and clinical management - PubMed

Cardiovascular involvement in ankylosing spondylitis and axial spondyloarthritis: epidemiology, mechanisms, and clinical management - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42232977/

Ankylosing spondylitis (AS) and axial spondyloarthritis (axSpA) are chronic inflammatory diseases primarily affecting the axial skeleton. Increasing evidence indicates that their impact extends beyond the musculoskeletal system and includes clinically...

Review highlights that ankylosing spondylitis and axial spondyloarthritis are associated with increased cardiovascular risk through chronic inflammation-driven endothelial dysfunction, atherosclerosis, and cardiac remodeling, supporting integrated cardiovascular surveillance and risk management.